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Servin Yeşil Günal*1Hikmet Saçmacı2
Şerife Saçmacı3
Meral Mirza4
Funda İpekten5
Original Research Article
Effect of heavy metals and sialic acid in multiple sclerosis
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Corresponding Author Email: sgunal(at)erciyes.edu.tr
Tel.: +90 352 437 52 79
Servin Yeşil Günal*1 |
Hikmet Saçmacı2 |
Şerife Saçmacı3 |
Meral Mirza4 |
Funda İpekten5 |
Article Number: irjpeh.18.015 | Pages: 114-120 | Vol.5 (7), November 2018 | DOI: https://doi.org/10.15739/irjpeh.18.015
Received: September 21, 2018 Accepted: November 16, 2018 Published: November 23, 2018
Abstract
The aim of this study is to investigate the effect of heavy metals, sialic acid and other environmental factors in patients with multiple sclerosis. Fifty-two multiple sclerosis patients and 41 healthy volunteers as the control group were included in the study. Fasting saliva and urine samples were taken to determine sialic acid and heavy metals respectively.The levels of Ag (p<0.001), Al (p<0.001), As (p<0.001), Ba (p<0.05), Cd (p<0.005), Cs (p<0.001), Cu (p<0.05), Mn (p<0.05), Ni (p<0.001), Pb (p<0.001), Rb (p<0.05), Sr (p<0.05), and sialic acid levels (p<0.001) were found significantly higher, Ti (p<0.05) and Fe (p<0.05) lower in MS patients compared to the control group. There was a significant relationship between sialic acid, heavy metals levels, vegetable consumption, bowel habits and multiple sclerosis group. In this study, it was found that high levels of sialic acid and heavy metals, less vegetable consumption and bad bowel habits were risk factors for multiple sclerosis.
Keywords: Vegetable consumption, heavy metals, multiple sclerosis, sialic acid, bad intestinal habits.
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