Original Research Article
Bacteriostatic and bactericidal activities of Acalypha indica L. plant leave extracts on bacteria shigella disenteriae Type 1 in vitro
Abdul Majid*1 and Frans Salesman2
1Lecturer of Pharmacy Faculty at Citra Bangsa University East Nusa Tenggara Indonesia.
2Professor in Public Health at Public Health Faculty at Citra Bangsa University, East Nusa Tenggara Indonesia.
*Corresponding Author Email: abdul311268(at)gmail.com
Tel. : +6281338886536
Abdul Majid |
Frans Salesman |
Article Number: irjpeh.21.033 | Pages: 304-309 | Vol. 8 (6), November 2021 | DOI: https://doi.org/10.15739/irjpeh.21.033
Received: September 15, 2021 Accepted: November 4, 2021 Published: November 22, 2021
Abstract
This study aimed to analyze the bacteriostatic and bactericidal activity of Acalypha indica L. extract against Shigella dysenteriae type 1 bacteria in vitro. This research is a laboratory experimental study consisting of six concentration treatments, namely: (K = 0/ml, P1 = 100/ml, P2 = 200/ml, P3 = 400/ml, P4 = 800/ml, P5 = 1600 mg/ml ), and five replications each. The results showed that the herbal extract of Acalypha indica L. was bacteriostatic (inhibiting) at a concentration of 400 mg/mm, and bactericidal (killing) the bacteria Shigella dysenteriae type 1, which was tested in vitro at a concentration of at least 800 mg/ml. It is necessary to study the effect of Acalypha indica L. herbal extract from Timor in the serum of Rattus norwegicus against bacteria that cause bloody diarrhea (EHEC O157:H7, and Shigella dysenteriae type 1), MRSA bacteria, and other pathogenic bacteria.
Keywords:
Extract, Acalypha Indica L, bacteriostatic, Shigella dysenteriae Type -1
How to Cite this Article
Majid A, Salesman F (2021). Bacteriostatic and bactericidal activities of Acalypha indica L. plant leave extracts on bacteria shigella disenteriae type 1 in vitro. Int. Res. J. Pub. Environ. Health 8(6):304-309.
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