Anti-diabetic role of edible mushroom Pleurotus sajor-caju: Cultivated on different types of bed materials

Abstract

The cultivation of mushroom on different non-conventional bed may have some nutritional and physiological benefit with an additional solution of environmental remediation. In the present study Pleurotus sajor-caju has been cultivated on three different bed materials i.e., Paddy straw (PS), Banana Leaf-base (BL) and Sugarcane trash (SC). In the present study some physiochemical characters and antidiabetic role of cultivated mushrooms has been studied. The Insulin receptor affinity of the phytocomponents of Pleurotus sajor-caju identified in the literature also have been studied by Autodock Vina. Results show that the moisture content, water solubility, water absorption and swelling capacity has been found highest in SC mushroom compare to PS and BL mushroom. The elevated FBS in STZ-induced diabetic rats was recovered after dietary supplementation of mushroom cultivated on each bed materials. Interestingly, the recovery of elevated FBS was faster in rats which were treated with BL mushroom compared to that of other two groups. The affinity of phytocomponents (C₂₂H₃₄O₄, C₁₄H₁₇O₉N, C₁₆H₃₂O₂, C₁₇H₃₄O, C₁₈H₃₂O₂) towards Insulin receptors (pdbID: 1CE6 and 1gag) shows a good affinity value, that supports the probable antidiabetic role of Pleurotus sajor-caju. Therefore, it can be concluded that the more effective antidiabetic role of Pleurotus sajor-caju may obtained when cultivated on Banana Leaf-base.

Keywords: Edible mushroom, paddy straw, sugarcane trash, banana leaf base, diabetes