Issues in Biological Sciences and Pharmaceutical Research
Vol. 2(4),pp. 035-039, April 2014
Article ID BSPR011/14/ 05 pages
Copyright © 2014 Author(s) retain the copyright of this article. Author(s) agree that this article remain permanently open access under the terms of the Creative Commons Attribution License 3.0 International License
Original Research Paper
Comparison in cognitive function in alzheimer’s disease and vascular dementia: Contributions to the differential diagnosis
Accepted 16 April, 2014
José Maria Montiel*1, Daniel Bartholomeu1, Juliana F. Cecato2, Mariana Gomes Giraldi2, José Eduardo Martinelli2
1University Center FIEO – Sao Paulo – Brazil.
2School of Medicine of Jundiai – Brazil.
*Corresponding Author Email: firstname.lastname@example.org
Dementia syndromes are characterized by the presence of deficit progressive cognitive function. Vascular dementia (VD) is the most prevalent between secondary dementias, ranking second among all dementia after Alzheimer’s disease (AD). The aim of this study was to evaluate the cognitive aspects of elderly patients with diagnoses of AD and VD. Participants were 256 elderly patients with mean age of 78 years and both sexes who received a diagnosis of Alzheimer’s disease by the Diagnostic Statistic Manual (DSM-IV) and National Institute of Neurological and Communicative Disorders and Stroke and the Alzheimer’s Disease and Related Disorders Association (NINCDS-ADRDA). The diagnosis of vascular dementia was done according to National Institute of Neurological Disorders and Stroke (NINDS) and the Association Internationale pour la Recherche et l’Enseignement en Neurosciences (NINCDS-AIREN). The results showed that the prevalence of AD was superior to VD, mean age increases the ratio DA/ VD, with women and people with lower education levels most affected. VD and AD patients have had similar cognitive abilities and VD patients exhibit more temporal orientation impairments than AD.
Key Words: Neuropsychological assessment, vascular dementia, alzheimer disease, cognition