International Research Journal of Public and Environmental Health
Vol.2 (11),pp. 191-196, November 2015
Available online at https://www.journalissues.org/IRJPEH/
Article 15/ID/JPRH084/ 06 pages
Author(s) agree that this article remain permanently open access under the terms of the Creative Commons Attribution License 4.0 International License.
Catalase activity in liver of Kafue lechwe (Kobus leche kafuensis) as biomarker for oxidative stress in pollution studies of Kafue flats, Zambia
E. M’kandawire, N. Saasa, K. M. Muzandu, G. S. Pandey, M. Nyirenda and M. Syakalima
1Department of Disease Control, University of Zambia, School of Veterinary Medicine, P.O. Box 32379, Lusaka 10101, Zambia.
2Department of Biomedical Sciences, University of Zambia, School of Veterinary Medicine, P.O. Box 32379, Lusaka, 10101, Zambia
3North-West University, Mafikeng Campus, Department of Animal Health, P/B X2046, Mmabatho 2735, South Africa.
*Corresponding Author E-mail: nsaasa(at)yahoo.co.uk, nsaasa(at)unza.zm
Catalase activity in liver of Kafue lechwe inhabiting the Kafue flats was measured. Research has shown that the Kafue flats have been exposed to heavy metals and pesticides posing a potential destruction to the inhabitants of the area. Studies on catalase activity in fish from the Kafue river have shown the potential of catalase activity as a biomarker of oxidative damage. However it is unclear how these findings apply on land and semi-aquatic Kafue lechwe within the flats. This study investigated the catalase activity in livers of Kafue lechwe in two game management areas (GMAs) within the flats. The mean catalase activity for Blue Lagoon and Lochnivar GMAs was 6.60 and 7.60 (K) respectively. Lochnivar showed a slightly higher mean level of activity although not significantly different from Blue lagoon (P = 0.36). The Pearson’s correlation, showed no association between age and activity (P = 0.37). There were no differences in activity between the sexes (P = 0.17). The activity levels were comparable to those determined in fish from the Kafue river suggesting that the Kafue lechwe could be exposed to similar pollutants in the environment and that catalase activity in Kafue lechwe could be a potential biomarker.
Key words: Catalase activity, kafue flats, kafue lechwe, oxidative stress, pollution