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I Okoh
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Issues in Biological Sciences and Pharmaceutical Research
Vol.3(1),pp.1-4, January 2015
ISSN 2350-1588
Article ID /15/BSPR001/04 page
Available online at https://www.journalissues.org/IBSPR/
DOI:http://dx.doi.org/10.15739/ibspr.006
Author(s) agree that this article remain permanently open access under the terms of the Creative Commons Attribution License 4.0 International License

 



Original Research Article

Prevalence of methicillin-resistant S. aureus (MRSA) among apparently healthy students in Afikpo, Ebonyi State, Nigeria

1Iroha Ifeanyichukwu, 1Okoh Inya, 2*Ejikeugwu Chika, 1Nwakaeze Emmanuel, 1Nwuzo Agabus, 1Afiukwa Ngozi, and 1Udu-Ibiam Esther

1Department of Applied Microbiology, Ebonyi State University, P.M.B 053, Abakaliki, Nigeria.
2Department of Pharmaceutical Microbiology and Biotechnology, Nnamdi Azikiwe University, P.M.B 5025, Awka, Nigeria.

*Corresponding Author Email: ejikeugwu_chika(at)yahoo.com
Tel.:+2348097684562



date Received:     date Accepted: January 29, 2015     date Published:


 Abstract

This study was carried out to determine the prevalence of community-acquired methicillin resistant Staphylococcus aureus (CA-MRSA) among apparently healthy students of Akanu Ibiam Federal Polytechnic Unwana, Afikpo, Ebonyi State, Nigeria. A total of 200 nasal swab samples were collected from apparently healthy students using sterile swab sticks and these were screened for the presence of S. aureus colonization using standard microbiology techniques. MRSA positive bacteria were detected phenotypically using oxacillin disk (1 µg). Antibiogram was determined by the disk diffusion method using ampicillin, cephalexin, clindamycin, ciprofloxacin, gentamicin, ofloxacin, perfloxacin, sparfloxacin, cefotaxime and vancomycin as per the guidelines of CLSI.  Out of the 200 nasal swab samples, 76 (38.0 %) isolates were isolated. MRSA positive bacteria were only detected in 33 (43.4 %) of the S. aureus isolates. High level of resistance was recorded amongst the MRSA positive bacteria to some commonly used antibiotics especially cefotaxime (100 %), ampicillin (100 %), clindamycin (9.0 %) and vancomycin (12 %). antibiotics. This study reported a high prevalence of MRSA bacteria amongst apparently healthy students. The irrational use of antibiotics especially in the community and without prescription spurs the development of resistance strains of bacteria. It is vital to detect antibiotic resistant bacteria (including MRSA bacteria) from both environmental and clinical samples in order to sustain the gains of antimicrobial chemotherapy.


Key words: Community acquired infections, MRSA, Resistance, Nigeria


Iroha et al