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W Genlin
Z Fuzhan
L Mao
W Zhirong
Z Ruofu
Y Huilin

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W Genlin
Z Fuzhan
L Mao
W Zhirong
Z Ruofu
Y Huilin

International Research Journal of Public and Environmental Health
Vol.3 (10),pp. 218-223, October, 2016
ISSN 2360-8803
Available online at https://www.journalissues.org/IRJPEH/
DOI:http://dx.doi.org/10.15739/irjpeh.16.028
Article 16/ID/JPRH053/06 pages
Author(s) agree that this article remain permanently open access under the terms of the Creative Commons Attribution License 4.0 International License.



Original Research Article

Characteristics of osteonecrosis in osteoporotic vertebral fractures and the efficacy of balloon kyphoplasty treatment

Genlin Wang, Fuzhan Zhang, Mao Li, Zhirong Wang, Ruofu Zhu and Huilin Yang

Department of Orthopedics, The First Affiliated Hospital of Soochow University, Suzhou, 215006, China.

*Corresponding Author Email: yhlsci(at)126.com

Tel: +086-512-67780101;
Fax:  +086-512-67780999.



date Received: July 28, 2016     date Accepted: September 20, 2016     date Published: October 14, 2016


 Abstract

Osteonecrosis in osteoporotic vertebral fractures (OVFs) may lead to a continued source of chronic pain and disability for patients. This study aims to describe the characteristics of the osteonecrosis in OVFs and the efficacy of balloon kyphoplasty (BKP) for the osteonecrosis. This was a prospective study of 61 patients with the osteonecrosis in OVFs who underwent BKP. Their mean age was 68 years (55 to 90). All the patients received radiography, MRI and CT examination before BKP, and were performed a histological analysis of biopsies obtained from OVFs. Efficacy was assessed by changes in anterior vertebral body height, a visual analogue pain scale and the Oswestry Disability Index at one day preoperative, two days postoperative and final follow-up assessments. All the patients had back pain more than six weeks before surgery. The back pain had a certain feature that was distinctly proportional to activity and position. 54% of the osteonecrosis showed intervertebral clefts in radiography, 73% of the osteonecrosis showed intervertebral clefts in CT. 98% of the osteonecrosis showed a well-defined signal intensity in the location of the osteonecrosis on T2-weighted and short tau inversion recovery (STIR) in MRI. Histological examination revealed osteonecrosis in the 61 patients. Significant improvements in all efficacy measures were observed at the postoperative versus preoperative assessments; no significant differences were observed between the postoperative and final follow-up assessments. The osteonecrosis in OVFs can be diagnosed according to the pattern of back pain and the imaging characteristics, especially MRI. BKP is one of minimally invasive, safe and effective procedures for the disease.


Key words: osteonecrosis, osteoporotic vertebral fractures, diagnosis, kyphoplast


Genlin et al