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T Ding
H Yang
JS Harrop
L Cheng
Y Zhang
M Maltenfort
Q Zhang

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T Ding
H Yang
JS Harrop
L Cheng
Y Zhang
M Maltenfort
Q Zhang

International Research Journal of Public and Environmental Health
Vol.3 (12),pp. 286-292, December 2016
ISSN 2360-8803
Available online at https://www.journalissues.org/IRJPEH/
DOI:http://dx.doi.org/10.15739/irjpeh.16.035
Article 16/ID/JPRH087/07 pages
Author(s) agree that this article remain permanently open access under the terms of the Creative Commons Attribution License 4.0 International License.



Original Research Article

Traumatic spondylolisthesis of the axis: Analysis of treatment and outcome in 40 cases

Tao Ding1*, Huilin Yang2, James S. Harrop3, Li Cheng1, Yafeng Zhang4, Mitchell Maltenfort3 and Qin Zhang1

1Department of Orthopaedics, Wuxi People ’s Hospital, Nanjing Medical University, Wuxi City, Jiangsu Province, China.
2Department of Orthopaedic Surgery, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China.
3Departments of Neurological and Orthopedic Surgery, Thomas Jefferson University Hospital, 909 Walnut Street, Philadelphia, PA 19107, USA.
4Department of Orthopaedics, Wuxi Affiliated Hospital of Nanjing University of Chinese Medicine,
Wuxi, Jiangsu, China.

*Corresponding Author E-mail: drdingtao(at)163.com



date Received: October 17, 2016     date Accepted: November 25, 2016     date Published: December 9, 2016


 Abstract

The current treatment of traumatic spondylolisthesis of the axis (TSA) is widely variable and management options include conservative options and surgical procedures. Unfortunately, the literature has several heterogeneous classification schemes, stability criteria and treatment algorithms thus making it difficult to derive clinical practice guidelines. This study seeks to identify predictors of successful outcome with conservative management. This retrospective study presents a consecutive series of 40 patients with TSA. Statistical analysis was performed to correlate clinical and radiographic measures with nonunion, residual neck pain and range of motion at final follow-up. Statistical analysis reveals Francis grade V having a significant correlation with non-union. Logistic regression analysis indicates that age (p=0.0107), initial translation (p=0.0189) and chronic tobacco use (p=0.0104) are significant risk factors for non-union in patients primarily treated with conservative management. Chronic tobacco use is the strongest predictor of non-union with an odds ratio of 65.99 (95% CI 2.39-21123.13). Initial translation was associated with an odds ratio of 1.62 (95% CI =1.08-3.15) and age had an odds ratio (per year) of 1.13 (95% CI = 1.02-1.39). The majority of TSA managed with conservative treatment achieved a satisfactory outcome, while early surgical fusion could be considered when risk factors exists.


Key words: axis fracture, traumatic spondylolisthesis, classification, treatment


Ding et al