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Issues in Biological Sciences and Pharmaceutical Research
Vol.3 (3), pp.21-32, March 2015
ISSN 2350-1588
Article ID BSPR/15/013/12 pages
Available online at
Author(s) agree that this article remain permanently open access under the terms of the Creative Commons Attribution License 4.0 International License

Original Research Article

Preliminary study on antimicrobial activity of friendly bacteria isolated from dairy products

F. Beatrice Damisa-Okorhi1,2* and Tega L. Ataikiru2

1University of Ibadan, Department of Botany and Microbiology, Oyo State Nigeria.
2School of Environmental Sciences, Federal University of Petroleum Resources Effurun Delta State Nigeria.

*Corresponding Author Email: damisabeatrice(at)

date Received:     date Accepted: March 20, 2015     date Published:


Lactic acid bacteria (LAB) are therefore excellent ambassadors for an often maligned microbial world, they are not only of major economic significance, but also of value in maintaining and promoting human health. However fifteen Lactic acid bacteria were isolated for the purpose of this work from milk and milk product, they were identified as Lactobacillus plantarum, Lactobacillus fermentum, Lactococcus lactis subspecie cremoris, Lactobacillus acidophilus, Lactobacillus brevis and Streptococcus thermophillus. Lactobacillus plantarum producd the highest quantity of Lactic acid at 72 hrs of incubation (2.89g/l) while Lactobacillus fermentum followed closely (1.11g/l),Lactococcus lactis subspecie cremoris had the highest quantity of diacetyl (1.72g/l) while Streptococcus thermophillus and Lactobacillus fermentum had the lowest quantity of 0.52g/l and 0.47g/l. At 72hrs of incubation Lactic acid produced the highest quantity of hydgrogen peroxide (1.91g/l) while Streptococcus thermophillus produced the lowest, the quantity of hydrogen peroxide increases up to 48hrs before declination sets in. Some alleged health benefits of consuming LAB, with Significant researches back up the claims that LAB enhance specific and nonspecific immune response, inhibit pathogen growth and translocation, stimulate gastrointestinal immunity, reduce chance of infection from common pathogens (Salmonella, Shigella), reduce risk of certain cancers (colon, bladder) Detoxify carcinogens Lower serum cholesterol concentrations improve urogenital health to name just but a few. However this paper tend to summarise the positive impact of LAB in health maintenance and disease prevention due to the antimicrobials produced by the organisms and extensive study that have been carried out by various researchers on these organism generally regarded as safe hence the name “The Good Guys”

Key words: GRAS LAB, Probiotic, Lactobacillus plantarum.

Damisa-Okorhi and Ataikiru