International Research Journal of Medicine and Biomedical Sciences
Vol.3 (2),pp. 10-14, November 2018
Available online at https://www.journalissues.org/IRJMBS/
Author(s) retain the copyright of this article. Author(s) agree that this article remain permanently open access under the terms of the Creative Commons Attribution License 4.0 International License.
Host factors in Campylobacter jejuni infection: A Review
*Abruquah, HH1&2, Oldfield, N. J.2, Worrall, K2., Wooldridge, K. G2., and Ala’Aldeen, D. A2.
1Department of Clinical Microbiology, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.
2The University of Nottingham, Nottingham, England.
*Corresponding Author Email: abruquahkow(at)gmail.com
Infection with C. jejuni is usually self-limiting but has varied manifestations depending on the host and the host‟s geographical location, thus, prompting the importance of host immune responses in determining disease. Fucosylated sugars in breast milk have been demonstrated not only to inhibit C. jejuni binding and infection but also prevent diarrhoea in infants, whilst the bactericidal effect of human serum has long been demonstrated, underlining the importance of host innate responses in containment of infection with C. jejuni.
Key words: Immune responses, infection, C. jejuni, host factor, human serum